</title> <original_language_title>Актуальные вопросы патогенетического лечения болезни Фабри в Российской Федерации</original_language_title> </titles> <contributors> <person_name sequence='first' contributor_role='author'> <given_name>S.</given_name> <surname>Moiseev</surname> </person_name> <person_name sequence='first' contributor_role='author'> <given_name>L.M.</given_name> <surname>Kuzenkova</…

The article provides an overview of current publications on the chemical structure, mechanism action and safety macrolide antibiotics. We conducted a search in PubMed Google Scholar databases for scientific articles published from 2010 to 2021. following key words were used: macrolides, antibiotics, erythromycin, clarithromycin, azithromycin, action, adverse drug reactions, toxicity. Macrolides are broad-spectrum antibiotics used treat wide range both local systemic infectious diseases. generally safe, although they can induce certain dose-dependent reactions.